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Caspase-Dependent Cleavage of DDX21 Suppresses Host Innate Immunity

Authors :
Wu, Wei
Qu, Yang
Yu, Shengqing
Wang, Sa
Yin, Yuncong
Liu, Qinfang
Meng, Chunchun
Liao, Ying
Ur Rehman, Zaib
Tan, Lei
Song, Cuiping
Qiu, Xusheng
Liu, Weiwei
Ding, Chan
Sun, Yingjie
Source :
mBio; June 2021, Vol. 12 Issue: 3
Publication Year :
2021

Abstract

Innate immunity serves as the first barrier against virus infection. DEAD (Glu-Asp-Ala-Glu) box RNA helicases, originally considered to be involved in RNA processing and RNA unwinding, have been shown to play an important role in antiviral innate immunity.

Details

Language :
English
ISSN :
21612129 and 21507511
Volume :
12
Issue :
3
Database :
Supplemental Index
Journal :
mBio
Publication Type :
Periodical
Accession number :
ejs57735523
Full Text :
https://doi.org/10.1128/mBio.01005-21