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Safety of Epicutaneous Immunotherapy in Peanut-Allergic Children: REALISE Randomized Clinical Trial Results

Authors :
Pongracic, Jacqueline A.
Gagnon, Rémi
Sussman, Gordon
Siri, Dareen
Oriel, Roxanne C.
Brown-Whitehorn, Terri
Green, Todd D.
Campbell, Dianne E.
Anvari, Sara
Berger, William E.
Bird, J. Andrew
Chan, Edmond S.
Cheema, Amarijit
Chinthrajah, Sharon
Chong, Hey
Dowling, Paul J.
Fineman, Stanley M.
Fleischer, David M.
Gonzalez-Reyes, Erika
Kim, Edwin H.
Lanser, Bruce J.
MacGinnitie, Andrew
Mehta, Hemalini
Petroni, Daniel
Rupp, Ned
Schneider, Lynda C.
Scurlock, Amy M.
Sher, Lawrence D.
Shreffler, Wayne G.
Sindher, Sayantani B.
Stillerman, Allan
Wood, Robert
Yang, William H.
Bois, Timothée
Sampson, Hugh A.
Bégin, Philippe
Source :
The Journal of Allergy and Clinical Immunology: In Practice; 20210101, Issue: Preprints
Publication Year :
2021

Abstract

Treatment options for peanut allergy are limited. In previous clinical trials, epicutaneous immunotherapy with a patch containing 250-μg peanut protein (Viaskin Peanut 250 μg [VP250]) was well tolerated and statistically superior to placebo in desensitizing peanut-allergic children.

Details

Language :
English
ISSN :
22132198
Issue :
Preprints
Database :
Supplemental Index
Journal :
The Journal of Allergy and Clinical Immunology: In Practice
Publication Type :
Periodical
Accession number :
ejs58364901
Full Text :
https://doi.org/10.1016/j.jaip.2021.11.017