Back to Search Start Over

A Predictive Endothelial-Leukemia Pre-Clinical Platform to Uncover Drug Vulnerabilities for Personalized Treatments

Authors :
Cappelli, Luca Vincenzo
Fiore, Danilo
Phillip, Jude M
Yoffe, Liron
Di Giacomo, Filomena
Hu, Yang
Kayembe, Clarisse
Ginsberg, Michael
Consolino, Lorena
Barcia Durán, José Gabriel
Zamponi, Nahuel
Melnick, Ari
Boccalatte, Francesco
Tam, Wayne
Elemento, Olivier
Chiaretti, Sabina
Guarini, Anna
Foa, Robin
Cerchietti, Leandro
Rafii, Shahin
Inghirami, Giorgio
Source :
Blood; November 2021, Vol. 138 Issue: 1, Number 1 Supplement 1 p704-704, 1p
Publication Year :
2021

Abstract

Background.T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive disease with few innovative treatment options. This is also contributed by the lack of models capable of capturing the complexity of the tumor and its microenvironment.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
138
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs58560739
Full Text :
https://doi.org/10.1182/blood-2021-153300