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The human HCLS1 gene maps to chromosome 3q13 by fluorescence in situ hybridization
- Source :
- Cytogenetics and Cell Genetics; January 1996, Vol. 72 Issue: 2-3 p175-176, 2p
- Publication Year :
- 1996
-
Abstract
- The human HSI gene (HCLS1, hematopoietic cell-specific Lyn substrate 1) expressed in human hematopoietic cells encodes a major substrate of protein-tyrosine kinase, p75<superscript>HS1</superscript>. This intracellular protein is involved in the signal transduction pathways that initiate at the antigen receptors of both B and T lymphocytes. Fluorescence in situ hybridization using a 2.0-kb cDNA and an 8.0-kb genomic DNA clone of HCLS1 as probes revealed that the gene maps to 3q13.
Details
- Language :
- English
- ISSN :
- 03010171 and 14219816
- Volume :
- 72
- Issue :
- 2-3
- Database :
- Supplemental Index
- Journal :
- Cytogenetics and Cell Genetics
- Publication Type :
- Periodical
- Accession number :
- ejs59079013
- Full Text :
- https://doi.org/10.1159/000134179