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Cambridge hybrid closed-loop algorithm in children and adolescents with type 1 diabetes: a multicentre 6-month randomised controlled trial

Authors :
Ware, Julia
Boughton, Charlotte K
Allen, Janet M
Wilinska, Malgorzata E
Tauschmann, Martin
Denvir, Louise
Thankamony, Ajay
Campbell, Fiona M
Wadwa, R Paul
Buckingham, Bruce A
Davis, Nikki
DiMeglio, Linda A
Mauras, Nelly
Besser, Rachel E J
Ghatak, Atrayee
Weinzimer, Stuart A
Hood, Korey K
Fox, D Steven
Kanapka, Lauren
Kollman, Craig
Sibayan, Judy
Beck, Roy W
Hovorka, Roman
Hovorka, R
Acerini, C L
Thankamony, A
Allen, J M
Boughton, C K
Dovc, K
Dunger, D B
Ware, J
Musolino, G
Tauschmann, M
Wilinska, M E
Hayes, J F
Hartnell, S
Slegtenhorst, S
Ruan, Y
Haydock, M
Mangat, J
Denvir, L
Kanthagnany, SK
Law, J
Randell, T
Sachdev, P
Saxton, M
Coupe, A
Stafford, S
Ball, A
Keeton, R
Cresswell, R
Crate, L
Cripps, H
Fazackerley, H
Looby, L
Navarra, H
Saddington, C
Smith, V
Verhoeven, V
Bratt, S
Khan, N
Moyes, L
Sandhu, K
West, C
Wadwa, R P
Alonso, G
Forlenza, G
Slover, R
Towers, L
Berget, C
Coakley, A
Escobar, E
Jost, E
Lange, S
Messer, L
Thivener, K
Campbell, F M
Yong, J
Metcalfe, E
Allen, M
Ambler, S
Waheed, S
Exall, J
Tulip, J
Buckingham, B A
Ekhlaspour, L
Maahs, D
Norlander, L
Jacobson, T
Twon, M
Weir, C
Leverenz, B
Keller, J
Davis, N
Kumaran, A
Trevelyan, N
Dewar, H
Price, G
Crouch, G
Ensom, R
Haskell, L
Lueddeke, LM
Mauras, N
Benson, M
Bird, K
Englert, K
Permuy, J
Ponthieux, K
Marrero-Hernandez, J
DiMeglio, L A
Ismail, H
Jolivette, H
Sanchez, J
Woerner, S
Kirchner, M
Mullen, M
Tebbe, M
Besser, R EJ
Basu, S
London, R
Makaya, T
Ryan, F
Megson, C
Bowen-Morris, J
Haest, J
Law, R
Stamford, I
Ghatak, A
Deakin, M
Phelan, K
Thornborough, K
Shakeshaft, J
Weinzimer, S A
Cengiz, E
Sherr, J L
Van Name, M
Weyman, K
Carria, L
Steffen, A
Zgorski, M
Sibayan, J
Beck, R W
Borgman, S
Davis, J
Rusnak, J
Hellman, A
Cheng, P
Kanapka, L
Kollman, C
McCarthy, C
Chalasani, S
Hood, K K
Hanes, S
Viana, J
Lanning, M
Fox, D S
Arreaza-Rubin, G
Eggerman, T
Green, N
Janicek, R
Gabrielson, D
Belle, S H
Castle, J
Green, J
Legault, L
Willi, S M
Wysham, C
Source :
The Lancet Digital Health; April 2022, Vol. 4 Issue: 4 pe245-e255, 11p
Publication Year :
2022

Abstract

Closed-loop insulin delivery systems have the potential to address suboptimal glucose control in children and adolescents with type 1 diabetes. We compared safety and efficacy of the Cambridge hybrid closed-loop algorithm with usual care over 6 months in this population.

Details

Language :
English
ISSN :
25897500
Volume :
4
Issue :
4
Database :
Supplemental Index
Journal :
The Lancet Digital Health
Publication Type :
Periodical
Accession number :
ejs59220338
Full Text :
https://doi.org/10.1016/S2589-7500(22)00020-6