Rosmarinic acid interferes with influenza virus A entry and replication by decreasing GSK3β and phosphorylated AKT expression levels

The purpose of this study was to examine the in vivoactivity of rosmarinic acid (RA) – a phytochemical with antioxidant, anti-inflammatory, and antiviral properties – against influenza virus (IAV). An antibody-based kinase array and different in vitrofunctional assays were also applied to identify the mechanistic underpinnings by which RA may exert its anti-IAV activity.