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Evidence for the toxicity of bidirectional transcripts and mitochondrial dysfunction in blood associated with small CGG expansions in the FMR1gene in patients with parkinsonism
- Source :
- Genetics in Medicine; May 2011, Vol. 13 Issue: 5 p392-399, 8p
- Publication Year :
- 2011
-
Abstract
- Our previous results showed that both gray zone and lower end premutation range (40–85 repeats) fragile X mental retardation 1 (FMR1) alleles were more common among males with parkinsonism than in the general population. This study aimed to determine whether these alleles have a significant role in the manifestations and pathogenesis of parkinsonian disorders.
Details
- Language :
- English
- ISSN :
- 10983600 and 15300366
- Volume :
- 13
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Genetics in Medicine
- Publication Type :
- Periodical
- Accession number :
- ejs59920466
- Full Text :
- https://doi.org/10.1097/GIM.0b013e3182064362