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Chromosome Abnormality in Rat Leukemia Induced by 7,12-Dimethylbenz[a]anthracene
- Source :
- Science; November 1967, Vol. 158 Issue: 3804 p1058-1059, 2p
- Publication Year :
- 1967
-
Abstract
- A high percentage of consistent chromosome abnormality, trisomy of the longest telocentric chromosome, was found in leukemias induced in rats of the Long-Evans strain by pulse doses of 7,12-dimethylbenz[a]anthracene. Cells with this abnormality were large, immature, and mononuclear and tended toward erythroblastic maturation.
Details
- Language :
- English
- ISSN :
- 00368075 and 10959203
- Volume :
- 158
- Issue :
- 3804
- Database :
- Supplemental Index
- Journal :
- Science
- Publication Type :
- Periodical
- Accession number :
- ejs60060573
- Full Text :
- https://doi.org/10.1126/science.158.3804.1058