Back to Search
Start Over
Abnormal collagen metabolism in cultured cells in osteogenesis imperfecta.
- Source :
- Proceedings of the National Academy of Sciences of the United States of America; February 1975, Vol. 72 Issue: 2 p586-589, 4p
- Publication Year :
- 1975
-
Abstract
- Cells obtained from normal human skin synthesize predominantly type I collogen in culture. Cells obtained from the skin of an infant with a severe form of osteogenesis imperfecta were found to synthesize as much type III as type I collagen. Decreased synthesis of type I collagen could explain the tissue fragility observed in this case.
Details
- Language :
- English
- ISSN :
- 00278424 and 10916490
- Volume :
- 72
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Periodical
- Accession number :
- ejs60428853
- Full Text :
- https://doi.org/10.1073/pnas.72.2.586