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Participant characteristics and safety outcomes of peanut oral immunotherapy in the RAMSES and ARC011 trials

Authors :
Ciaccio, Christina
Goldsobel, Alan B.
Anagnostou, Aikaterini
Beyer, Kirsten
Casale, Thomas B.
Deschildre, Antoine
Fernández-Rivas, Montserrat
Hourihane, Jonathan O'B.
Krawiec, Marta
Lieberman, Jay
Scurlock, Amy M.
Vickery, Brian P.
Smith, Alex
Tilles, Stephen A.
Adelman, Daniel C.
Brown, Kari R.
Assa'ad, Amal H.
Bernstein, David I.
Bird, J. Andrew
Carr, Tara F.
Carr, Warner W.
Cheema, Amarjit S.
Corren, Jonathan
Darter, Amy Liebl
Dorsey, Morna J.
Fineman, Stanley M.
Fleischer, David M.
Fritz, Stephen B.
Gogate, Shaila U.
Greiner, Alexander N.
Hampel, Frank C.
Jacobs, Joshua S.
Jain, Sanjeev
Jarvinen-Seppo, Kirsi
Jeong, David K.
Johnston, Douglas T.
Kachru, Rita
Kim, Edwin H.
Koleilat, Majed
Lanser, Bruce J.
Leonard, Stephanie A.
Maier, Mary C.
Manning, Michael E.
Mansfield, Lyndon E.
Matz, Jonathan
Nadeau, Kari
Ohayon, Jason A.
Perez, Elena
Petroni, Daniel H.
Pollard, Stephen J.
Ponda, Punita
Portnoy, Jay M.
Rachid, Rima
Ratner, Paul H.
Robison, Rachel
Rupp, Ned T.
Sanders, Georgiana M.
Sharma, Hemant P.
Sher, Ellen R.
Sher, Lawrence D.
Sher, Mandel
Shreffler, Wayne G.
Siri, Dareen D.
Skolnick, Helen S.
Soong, Weily
Soteres, Daniel F.
Spergel, Jonathan M.
Stillerman, Allan
Sussman, Gordon L.
Tam, Jonathan
Varshney, Pooja
Waserman, Susan
Windom, Hugh H.
Wood, Robert
Yang, William H.
Source :
Annals of Allergy, Asthma & Immunology; December 2022, Vol. 129 Issue: 6 p758-768.e4
Publication Year :
2022

Abstract

Clinical trials (PALISADE [ARC003], ARTEMIS [ARC010]) proving efficacy and safety of peanut (Arachis hypogaea) allergen powder-dnfp (PTAH) have used double-blind, placebo-controlled food challenges (DBPCFCs) to screen for eligibility and to evaluate efficacy. In routine clinical practice, individuals with peanut allergy do not always undergo food challenges to confirm diagnosis or determine candidacy for treatment.

Details

Language :
English
ISSN :
10811206
Volume :
129
Issue :
6
Database :
Supplemental Index
Journal :
Annals of Allergy, Asthma & Immunology
Publication Type :
Periodical
Accession number :
ejs61918812
Full Text :
https://doi.org/10.1016/j.anai.2022.07.033
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