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Tumor oncogene (KRAS) status and risk of venous thrombosis in patients with metastatic colorectal cancer

Authors :
Ades, S.
Kumar, S.
Alam, M.
Goodwin, A.
Weckstein, D.
Dugan, M.
Ashikaga, T.
Evans, M.
Verschraegen, C.
Holmes, C.E.
Source :
Journal of Thrombosis and Haemostasis; June 2015, Vol. 13 Issue: 6 p998-1003, 6p
Publication Year :
2015

Abstract

Patients with metastatic colon cancer (mCRC) are at increased risk of venous thromboembolism (VTE). Limited preclinical data suggest that the oncogene (KRAS) mutational status of the tumor represents a plausible clinical link to systemic hypercoagulability in cancer patients.

Details

Language :
English
ISSN :
15387933 and 15387836
Volume :
13
Issue :
6
Database :
Supplemental Index
Journal :
Journal of Thrombosis and Haemostasis
Publication Type :
Periodical
Accession number :
ejs62067164
Full Text :
https://doi.org/10.1111/jth.12910