Health-related Quality of Life of Patients Treated With Different Fractionation Schedules for Early Prostate Cancer Compared to the Age-standardized General Male Population

•The overall health-related quality of life (HRQoL) of the patients with an early prostate cancer treated with modern image guided RT techniques and without hormonal treatment is equal at 3 years after treatment to the age-standardized general male population measured with the 15D instrument.•More support to the patients with an early prostate cancer should be given in mental health issues at the beginning of treatment and in the sexual issues after the treatment.•The HRQoL of the patients with an early prostate cancer treated with 3 different radiotherapy fractionation was measured with the 15D instrument and The Functional Assessment of Cancer Therapy-Prostate (FACT-P) questionnaire and compared. Continuation to treat with stereotactic body radiotherapy seems rational regarding to the HRQoL results.