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Preclinical studies of a factor X activator and a phase 1 trial for hemophilia patients with inhibitors

Authors :
Liu, Wei
Xue, Feng
Fu, Rongfeng
Ding, Bingjie
Li, Mengjuan
Sun, Ting
Chen, Yunfei
Liu, Xiaofan
Ju, Mankai
Dai, Xinyue
Wu, Quanrui
Zhou, Zan
Yu, Jiaojiao
Wang, Xiaomin
Zhu, Qing
Zhou, Hu
Yang, Renchi
Zhang, Lei
Source :
Journal of Thrombosis and Haemostasis; 20230101, Issue: Preprints
Publication Year :
2023

Abstract

Bleeding episodes in hemophiliacs with inhibitors are difficult to control. STSP-0601, a specific factor X (FX) activator purified from the venom of Daboia russelii siamensis, has been developed.

Details

Language :
English
ISSN :
15387933 and 15387836
Issue :
Preprints
Database :
Supplemental Index
Journal :
Journal of Thrombosis and Haemostasis
Publication Type :
Periodical
Accession number :
ejs62253126
Full Text :
https://doi.org/10.1016/j.jtha.2023.01.040