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RNA splicing factor Rbm25underlies heterogeneous preleukemic clonal expansion in mice
- Source :
- Blood; June 2023, Vol. 141 Issue: 24 p2961-2972, 12p
- Publication Year :
- 2023
-
Abstract
- •Tet2knockout in mice induces heterogeneous clonal expansion associated with an aberrant expression of RNA splicing factors.•Repression of RNA splicing factor Rbm25triggers clonal expansion of Tet2knockout hematopoietic cells in vitro and in vivo.
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Volume :
- 141
- Issue :
- 24
- Database :
- Supplemental Index
- Journal :
- Blood
- Publication Type :
- Periodical
- Accession number :
- ejs62660883
- Full Text :
- https://doi.org/10.1182/blood.2023019620