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Endovascular treatment versus no endovascular treatment after 6–24 h in patients with ischaemic stroke and collateral flow on CT angiography (MR CLEAN-LATE) in the Netherlands: a multicentre, open-label, blinded-endpoint, randomised, controlled, phase 3 trial

Authors :
Olthuis, Susanne G H
Pirson, F Anne V
Pinckaers, Florentina M E
Hinsenveld, Wouter H
Nieboer, Daan
Ceulemans, Angelique
Knapen, Robrecht R M M
Robbe, M M Quirien
Berkhemer, Olvert A
van Walderveen, Marianne A A
Lycklama à Nijeholt, Geert J
Uyttenboogaart, Maarten
Schonewille, Wouter J
van der Sluijs, P Matthijs
Wolff, Lennard
van Voorst, Henk
Postma, Alida A
Roosendaal, Stefan D
van der Hoorn, Anouk
Emmer, Bart J
Krietemeijer, Menno G M
van Doormaal, Pieter-Jan
Roozenbeek, Bob
Goldhoorn, Robert-Jan B
Staals, Julie
de Ridder, Inger R
van der Leij, Christiaan
Coutinho, Jonathan M
van der Worp, H Bart
Lo, Rob T H
Bokkers, Reinoud P H
van Dijk, Ewoud I
Boogaarts, Hieronymus D
Wermer, Marieke J H
van Es, Adriaan C G M
van Tuijl, Julia H
Kortman, Hans G J
Gons, Rob A R
Yo, Lonneke S F
Vos, Jan-Albert
de Laat, Karlijn F
van Dijk, Lukas C
van den Wijngaard, Ido R
Hofmeijer, Jeannette
Martens, Jasper M
Brouwers, Paul J A M
Bulut, Tomas
Remmers, Michel J M
de Jong, Thijs E A M
den Hertog, Heleen M
van Hasselt, Boudewijn A A M
Rozeman, Anouk D
Elgersma, Otto E H
van der Veen, Bas
Sudiono, Davy R
Lingsma, Hester F
Roos, Yvo B W E M
Majoie, Charles B L M
van der Lugt, Aad
Dippel, Diederik W J
van Zwam, Wim H
van Oostenbrugge, Robert J
Source :
The Lancet; April 2023, Vol. 401 Issue: 10385 p1371-1380, 10p
Publication Year :
2023

Abstract

Endovascular treatment for anterior circulation ischaemic stroke is effective and safe within a 6 h window. MR CLEAN-LATE aimed to assess efficacy and safety of endovascular treatment for patients treated in the late window (6–24 h from symptom onset or last seen well) selected on the basis of the presence of collateral flow on CT angiography (CTA).

Details

Language :
English
ISSN :
01406736 and 1474547X
Volume :
401
Issue :
10385
Database :
Supplemental Index
Journal :
The Lancet
Publication Type :
Periodical
Accession number :
ejs62867001
Full Text :
https://doi.org/10.1016/S0140-6736(23)00575-5
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