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Continuous-Flow Ventricular Assist Device Support in Adult Congenital Heart Disease: A 15-Year, Multicenter Experience of Temporary and Durable Support
- Source :
- ASAIO Journal: A Peer-Reviewed Journal of the American Society for Artificial Internal Organs; May 2023, Vol. 69 Issue: 5 p429-437, 9p
- Publication Year :
- 2023
-
Abstract
- Heart failure (HF) is common in adult congenital heart disease (ACHD) patients; however, use of continuous-flow ventricular assist devices (CF-VADs) remains rare. We reviewed outcomes of patients with congenital heart disease greater than or equal to 18 years of age at the time of CF-VAD implant at the affiliated pediatric and adult institutions between 2006 and 2020. In total, 18 ACHD patients (15 with great anatomical complexity) received 21 CF-VADs. Six patients (median age 34 years) received seven percutaneous CF-VADs with a median duration of support of 20 days (3–44 days) with all patients survived to hospital discharge and two patients were bridged to durable CF-VADs. Fourteen patients (median age 38 years) received durable CF-VADs. Thirteen patients (93%) survived to hospital discharge and the median duration of support was 25.8 months (6.4–52.1 months). Estimated survival on durable CF-VAD at 1, 3, and 5 years was 84%, 72%, and 36%, respectively. Three patients were successfully bridged to transplantation. Device-related complications include cerebrovascular accident (n = 5), driveline infection (n = 3), device infection requiring chronic antibiotic therapy (n = 4), gastrointestinal bleeding (n = 6), and presumed pump thrombosis (n = 5). These results show percutaneous and durable CF-VADs can support ACHD patients with advanced HF.
Details
- Language :
- English
- ISSN :
- 10582916 and 1538943X
- Volume :
- 69
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- ASAIO Journal: A Peer-Reviewed Journal of the American Society for Artificial Internal Organs
- Publication Type :
- Periodical
- Accession number :
- ejs62945080
- Full Text :
- https://doi.org/10.1097/MAT.0000000000001853