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NLRC5 potentiates anti-tumor CD8+T cells responses by activating interferon-β in endometrial cancer

Authors :
Zhang, Jing
Guo, Bao
Chen, Jia-Hua
Liu, Xiao-Jing
Zhang, Jun-Hui
Zhu, Hai-Qing
Wang, Wen-Yan
Tang, Zhen-Hai
Wei, Bing
Cao, Yun-Xia
Zhan, Lei
Source :
Translational Oncology; October 2023, Vol. 36 Issue: 1
Publication Year :
2023

Abstract

•NLRC5 potentiates antitumor responses of CD8+T cells against EC.•IFN-β promotes immunosurveillance of EC by activating CD8+T cells.•NLRC5 potentiates antitumor responses of CD8+T cells to EC by activating IFN-β.

Details

Language :
English
ISSN :
19447124 and 19365233
Volume :
36
Issue :
1
Database :
Supplemental Index
Journal :
Translational Oncology
Publication Type :
Periodical
Accession number :
ejs63646804
Full Text :
https://doi.org/10.1016/j.tranon.2023.101742