UpStreAm doxycycline in ST-eLeVation myocArdial infarction: targetinG infarct hEaling and ModulatIon (SALVAGE-MI trial)

Graphical AbstractCMR final infarct size adjusted for area-at-risk; myocardial salvage index; and LV remodelling in doxycycline- and placebo-treated patients (A& B) and in LAD subgroup (C& D). fIS/AAR, final infarct size adjusted for area-at-risk; MSI, myocardial salvage index; ΔLVEDVi, change in left ventricular end-diastolic volume index and the acute infarct size; LAD, left anterior descending coronary artery. afIS/AAR is multiplied by 100 for graphical presentation.