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Gata2noncoding genetic variation as a determinant of hematopoietic stem/progenitor cell mobilization efficiency

Authors :
Soukup, Alexandra A.
Bresnick, Emery H.
Source :
Blood Advances; December 2023, Vol. 7 Issue: 24 p7564-7575, 12p
Publication Year :
2023

Abstract

•Noncoding Gata2genetic variation reduces efficacy of single and multiagent clinical regimens to mobilize HSPCs.•Noncoding Gata2genetic variation abrogates polyvinyl alcohol–induced hematopoietic stem/progenitor cell expansion.

Details

Language :
English
ISSN :
24739529 and 24739537
Volume :
7
Issue :
24
Database :
Supplemental Index
Journal :
Blood Advances
Publication Type :
Periodical
Accession number :
ejs64337760
Full Text :
https://doi.org/10.1182/bloodadvances.2023011003