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10-day decitabine versus 3 + 7 chemotherapy followed by allografting in older patients with acute myeloid leukaemia: an open-label, randomised, controlled, phase 3 trial
- Source :
- The Lancet Haematology; November 2023, Vol. 10 Issue: 11 pe879-e889, 11p
- Publication Year :
- 2023
-
Abstract
- Many older patients with acute myeloid leukaemia die or cannot undergo allogeneic haematopoietic stem-cell transplantation (HSCT) due to toxicity caused by intensive chemotherapy. We hypothesised that replacing intensive chemotherapy with decitabine monotherapy could improve outcomes.
Details
- Language :
- English
- ISSN :
- 23523026
- Volume :
- 10
- Issue :
- 11
- Database :
- Supplemental Index
- Journal :
- The Lancet Haematology
- Publication Type :
- Periodical
- Accession number :
- ejs64384445
- Full Text :
- https://doi.org/10.1016/S2352-3026(23)00273-9