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A comprehensive analysis of the expression, immune infiltration, prognosis and partial experimental validation of CHST family genes in gastric cancer

Authors :
Zhan, Jinbo
Zhou, Ling
Zhang, Hongjiao
Zhou, Juanjuan
He, Yan
Hu, Tingting
Le, Yi
Lin, Yun
Wang, Jingru
Yu, Haiming
Liu, Yawen
Xiang, Xiaojun
Source :
Translational Oncology; February 2024, Vol. 40 Issue: 1
Publication Year :
2024

Abstract

•Expounding the expression, immunoinfiltration and prognostic significance of CHSTs in gastric cancer.•Constructing a prognostic nomogram with CHST14 as a key molecule in gastric cancer.•CHST14 promotes gastric cancer cell proliferation, invasion, migration and EMT through the activation of the Wnt/β-catenin signaling pathway.

Details

Language :
English
ISSN :
19447124 and 19365233
Volume :
40
Issue :
1
Database :
Supplemental Index
Journal :
Translational Oncology
Publication Type :
Periodical
Accession number :
ejs64573295
Full Text :
https://doi.org/10.1016/j.tranon.2023.101843