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Positron Emission Tomography Evaluation in Relapsed/Refractory B-Cell Lymphoma Patients Treated with Anti-19 Chimeric Antigen Receptor (CAR) T-Cells in the CART-SIE Observational Study

Authors :
Dodero, Anna
Guidetti, Anna
Chiappella, Annalisa
Ljevar, Silva
Zinzani, Pier Luigi
Casadei, Beatrice
Bramanti, Stefania
Santoro, Armando
Chiusolo, Patrizia
Di Rocco, Alice
Di Palma, Martina
Tisi, Maria Chiara
Cutini, Ilaria
Carrabba, Matteo Giovanni
Musso, Maurizio
Martino, Massimo
Barbui, Anna Maria
Novo, Mattia
Grillo, Giovanni
Battista, Marta Lisa
Zanni, Manuela
Arcaini, Luca
Miceli, Rosalba
Carniti, Cristiana
Corradini, Paolo
Source :
Blood; November 2023, Vol. 142 Issue: 1, Number 1 Supplement 1 p3517-3517, 1p
Publication Year :
2023

Abstract

Background: CD19 direct chimeric antigen receptor (CAR) T-cell therapy is an efficacious therapy for patients (pts) affected by relapsed/refractory (R/R) large B-cell lymphomas (LBCL). The role of early evaluation by Positron emission tomography/computed tomography (PET/CT) is still undefined. The study's objective was to analyze the role of early PET/CT according to histology and CAR T-cell product administered.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
142
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs64577539
Full Text :
https://doi.org/10.1182/blood-2023-184614