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Platelets mediate the clearance of senescent red blood cells by forming prophagocytic platelet-cell complexes
- Source :
- Blood; February 2024, Vol. 143 Issue: 6 p535-547, 13p
- Publication Year :
- 2024
-
Abstract
- •Senescent RBCs are bound to platelets, forming P-RBC complexes that are selectively consumed by erythrophagocytes.•A sufficient supply of platelets is required to maintain efficient complex-dependent clearance of senescent RBCs.
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Volume :
- 143
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Blood
- Publication Type :
- Periodical
- Accession number :
- ejs64701766
- Full Text :
- https://doi.org/10.1182/blood.2023021611