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Post-transplant cyclophosphamide-based graft-versus-host disease prophylaxis in HLA-matched and haploidentical donor transplants for patients with Hodgkin lymphoma: a comparative study of the LWP EBMT.

Authors :
Montoro, J
Boumendil, A
Finel, H
Bramanti, S
Castagna, L
Blaise, D
Dominietto, A
Kulagin, A
Yakoub-Agha, I
Tbakhi, A
Solano, C
Giebel, S
Gulbas, Z
López Corral, L
Pérez-Simón, J.A
Díez Martín, J.L
Sanz, J
Farina, L
Koc, Y
Socié, G
Arat, M
Jurado, M
Bermudez, A
Labussière-Wallet, H
Villalba, M
Ciceri, F
Martinez, C
Nagler, A
Sureda, A
Glass, B
Source :
Transplantation and Cellular Therapy; 20230101, Issue: Preprints
Publication Year :
2023

Abstract

•HSCT efficacy and safety in Hodgkin lymphoma using HLA-matched and haploidentical donors with PTCy GVHD prophylaxis.•HLA-matched had lower NRM, resulting in higher OS compared to haploidentical.•Our study supports HLA-matched donors with PTCy GVHD prophylaxis over haploidentical donors.

Details

Language :
English
ISSN :
26666375 and 26666367
Issue :
Preprints
Database :
Supplemental Index
Journal :
Transplantation and Cellular Therapy
Publication Type :
Periodical
Accession number :
ejs64755999
Full Text :
https://doi.org/10.1016/j.jtct.2023.11.021