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Dupilumab Improves Lung Function Parameters in Pediatric Type 2 Asthma: VOYAGE Study

Authors :
Bacharier, Leonard B.
Guilbert, Theresa W.
Katelaris, Constance H.
Deschildre, Antoine
Phipatanakul, Wanda
Liu, Dongfang
Altincatal, Arman
Mannent, Leda P.
Amin, Nikhil
Laws, Elizabeth
Akinlade, Bolanle
Jacob-Nara, Juby A.
Deniz, Yamo
Rowe, Paul J.
Lederer, David J.
Hardin, Megan
Source :
The Journal of Allergy and Clinical Immunology: In Practice; 20230101, Issue: Preprints
Publication Year :
2023

Abstract

Uncontrolled asthma in growing children can impair lung growth that may lead to adverse complications in later life. Dupilumab, a human monoclonal antibody, blocks the shared receptor for IL-4 and IL-13, key drivers of type 2 inflammation.

Details

Language :
English
ISSN :
22132198
Issue :
Preprints
Database :
Supplemental Index
Journal :
The Journal of Allergy and Clinical Immunology: In Practice
Publication Type :
Periodical
Accession number :
ejs64849199
Full Text :
https://doi.org/10.1016/j.jaip.2023.12.006