Back to Search Start Over

Elotuzumab, lenalidomide, bortezomib, dexamethasone, and autologous haematopoietic stem-cell transplantation for newly diagnosed multiple myeloma (GMMG-HD6): results from a randomised, phase 3 trial

Authors :
Mai, Elias K
Goldschmidt, Hartmut
Miah, Kaya
Bertsch, Uta
Besemer, Britta
Hänel, Mathias
Krzykalla, Julia
Fenk, Roland
Schlenzka, Jana
Munder, Markus
Dürig, Jan
Blau, Igor W
Huhn, Stefanie
Hose, Dirk
Jauch, Anna
Kunz, Christina
Mann, Christoph
Weinhold, Niels
Scheid, Christof
Schroers, Roland
von Metzler, Ivana
Schieferdecker, Aneta
Thomalla, Jörg
Reimer, Peter
Mahlberg, Rolf
Graeven, Ullrich
Kremers, Stephan
Martens, Uwe M
Kunz, Christian
Hensel, Manfred
Benner, Axel
Seidel-Glätzer, Andrea
Weisel, Katja C
Raab, Marc S
Salwender, Hans J
Adrian, Nicole
Bernhard, Helga
Böck, Hans-Peter
Bolling, Claus
Dingeldein, Gerrit
Emde, Till-Oliver
Ferstl, Barbara
Fietz, Thomas
Fronhoffs, Stefan
Fuhrmann, Stephan
Fuxius, Stefan
Geer, Thomas
Görner, Martin
Guenther, Barbara
Hartmann, Frank
Heilmeier, Bernhard
Heinsch, Michael
Hoffmann, Martin
Holderried, Tobias A.W.
Klein, Stefan
Klump, Martin
Knauf, Wolfgang
La Rosée, Paul
Lange, Elisabeth
Lindemann, Walter
Lopez, Roderico
Mayer, Frank
Nückel, Holger
Papesch, Eva
Procaccianti, Maria
Reichart, Alexander
Rummel, Mathias
Scheuer, Lars
Schmitt, Hans-Roland
Staib, Peter
Steiniger, Heike
Tischler, Hans-Joachim
Ulshöfer, Thomas
Verbeek, Walter
Wacker, Alexander
Zirpel, Iris
Source :
The Lancet Haematology; February 2024, Vol. 11 Issue: 2 pe101-e113, 13p
Publication Year :
2024

Abstract

The aim of this trial was to investigate the addition of the anti-SLAMF7 monoclonal antibody elotuzumab to lenalidomide, bortezomib, and dexamethasone (RVd) in induction and consolidation therapy as well as to lenalidomide maintenance treatment in transplant-eligible patients with newly diagnosed multiple myeloma.

Details

Language :
English
ISSN :
23523026
Volume :
11
Issue :
2
Database :
Supplemental Index
Journal :
The Lancet Haematology
Publication Type :
Periodical
Accession number :
ejs65355163
Full Text :
https://doi.org/10.1016/S2352-3026(23)00366-6