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Early CD4 and B Cell Immune Reconstitution As Predictors of Outcomes in T Cell Depleted Allogeneic Hematopoietic Cell Transplantation
- Source :
- Transplantation and Cellular Therapy; February 2024, Vol. 30 Issue: 2, Number 2 Supplement 1 pS316-S317, 2p
- Publication Year :
- 2024
-
Abstract
- We recently showed in a large pediatric tri-institutional cohort of patients receiving a first allogeneic hematopoietic cell transplantation (allo-HCT) for a hematologic malignancy, that, in addition to recovery of CD4 > 50 cells/uL, also recovery of B cells > 25 cells/uL was found to be a predictor for outcomes. The impact of B cell immune reconstitution (IR) in a purely ex vivoT-cell depleted (TCD) setting has not been described.
Details
- Language :
- English
- ISSN :
- 26666375 and 26666367
- Volume :
- 30
- Issue :
- 2, Number 2 Supplement 1
- Database :
- Supplemental Index
- Journal :
- Transplantation and Cellular Therapy
- Publication Type :
- Periodical
- Accession number :
- ejs65462843
- Full Text :
- https://doi.org/10.1016/j.jtct.2023.12.436