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Health-related quality of life in patients with triple-class exposed relapsed and refractory multiple myeloma treated with idecabtagene vicleucel or standard regimens: patient-reported outcomes from the phase 3, randomised, open-label KarMMa-3 clinical trial

Authors :
Delforge, Michel
Patel, Krina
Eliason, Laurie
Dhanda, Devender
Shi, Ling
Guo, Shien
Marshall, Thomas S
Arnulf, Bertrand
Cavo, Michele
Nooka, Ajay
Manier, Salomon
Callander, Natalie
Giralt, Sergio
Einsele, Hermann
Ailawadhi, Sikander
Popa McKiver, Mihaela
Cook, Mark
Rodríguez-Otero, Paula
Source :
The Lancet Haematology; March 2024, Vol. 11 Issue: 3 pe216-e227, 12p
Publication Year :
2024

Abstract

Chimeric antigen receptor T-cell therapy idecabtagene vicleucel (ide-cel) showed significantly improved progression-free survival compared with standard regimens in adults with relapsed and refractory multiple myeloma who had received two to four previous regimens in the ongoing phase 3 KarMMa-3 trial (NCT03651128). This study analysed patient-reported outcomes (PROs), a KarMMa-3 secondary endpoint.

Details

Language :
English
ISSN :
23523026
Volume :
11
Issue :
3
Database :
Supplemental Index
Journal :
The Lancet Haematology
Publication Type :
Periodical
Accession number :
ejs65640088
Full Text :
https://doi.org/10.1016/S2352-3026(24)00005-X