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Axicabtagene ciloleucel vs standard of care in second-line large B-cell lymphoma: outcomes by metabolic tumor volume

Authors :
Locke, Frederick L.
Oluwole, Olalekan O.
Kuruvilla, John
Thieblemont, Catherine
Morschhauser, Franck
Salles, Gilles
Rowe, Steven P.
Vardhanabhuti, Saran
Winters, Joshua
Filosto, Simone
To, Christina
Cheng, Paul
Schupp, Marco
Korn, Ronald
Kersten, Marie José
Source :
Blood; June 2024, Vol. 143 Issue: 24 p2464-2473, 10p
Publication Year :
2024

Abstract

•MTV affected outcomes of second-line treatment in both arms, and axi-cel improved EFS and PFS over standard care, irrespective of MTV.•Baseline MTV associated with grade ≥3 CRS and neurologic events after axi-cel treatment.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
143
Issue :
24
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs65953109
Full Text :
https://doi.org/10.1182/blood.2023021620