Impact of hematopoietic cell transplantation on myocardial fibrosis in young patients with sickle cell disease

Authors :: Sharma, Akshay
Selukar, Subodh
Bi, Yu
Merlocco, Anthony
Morin, Cara E.
Goode, Chris
Rai, Parul
Towbin, Jeffrey A.
Hankins, Jane S.
Gottschalk, Stephen
Triplett, Brandon
Johnson, Jason N.
Source :: Blood; August 2024, Vol. 144 Issue: 6 p672-675, 4p
Publication Year :: 2024
Abstract: Serial cardiovascular magnetic resonance evaluation of children and young adults with SCD who underwent hematopoietic cell transplantation showed mean ECV, representing diffuse myocardial fibrosis, decreased 3.4% from baseline to 12 months posttransplantation. This trial was registered at www.clinicaltrials.govas #NCT04362293.

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