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Electrophysiological expression of endothelin and angiotensin receptors in Xenopusoocytes injected with rat heart mRNA

Authors :
Lory, Philippe
Richard, Sylvain
Rassendren, François A.
Tiaho, François
Nargeot, Joël
Source :
FEBS Letters; January 1989, Vol. 258 Issue: 2 p289-292, 4p
Publication Year :
1989

Abstract

Functional endothelin and angiotensin receptors have been expressed in Xenopusoocyte following the microinjection of rat heart mRNA. Under voltage clamp conditions, application of these peptides clearly induced oscillatory Ca 2+-activated chloride currents in a dose-dependent manner. In addition, no direct modulation of expressed or native cardiac Ca channels was observed.

Details

Language :
English
ISSN :
00145793
Volume :
258
Issue :
2
Database :
Supplemental Index
Journal :
FEBS Letters
Publication Type :
Periodical
Accession number :
ejs66312686
Full Text :
https://doi.org/10.1016/0014-5793(89)81676-X