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Risk factors of mortality following hospital admission for Crohn'sdisease: A cohort study at a tertiary referral center in Taiwan

Authors :
Huang, Po‐Han
Lin, Wey‐Ran
Le, Puo‐Hsien
Lin, Cheng‐Yu
Chen, Chun‐Wei
Wu, Ren‐Chin
Hsu, Jun‐Te
Tsai, Wen‐Sy
Lai, Ming‐Wei
Hsieh, Sen‐Yung
Su, Ming‐Yao
Chiu, Cheng‐Tang
Kuo, Chia‐Jung
Source :
Advances in Digestive Medicine; June 2024, Vol. 11 Issue: 2 p81-87, 7p
Publication Year :
2024

Abstract

The prevalence and incidence of Crohn's disease (CD) in Asia is rising, and it is important to know the risk factors of mortality. In our study, CD patients diagnosed and treated in the Chang Gung Memorial Hospital Linkou branch were enrolled from January 1989 to October 2019. The collected data included age, sex, disease duration, location and behavior of the disease, biochemical parameters at admission, medication history, surgical history, and comorbidities. The mean age at diagnosis was 35.7 ± 16.1 years old and the male‐to‐female ratio was 2.4. The penetrating type of CD was the most common (41.3%) of disease behavior. The ileocolonic area is the most common location of disease involvement (79%). 7.7% of patients had low serum albumin levels (<3 g/dL). 16.8% of patients had hemoglobin levels less than 10 g/dL. Of the patients included, 4 died during the follow‐up period. Low serum albumin levels at admission (p= .0307) are an independent predictor for mortality. In conclusion, it is important in perioperative care, especially for CD patients with hypoalbuminemia.

Details

Language :
English
ISSN :
23519797 and 23519800
Volume :
11
Issue :
2
Database :
Supplemental Index
Journal :
Advances in Digestive Medicine
Publication Type :
Periodical
Accession number :
ejs66659250
Full Text :
https://doi.org/10.1002/aid2.13379