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Krüppel-like factor 12 decreases progestin sensitivity in endometrial cancer by inhibiting the progesterone receptor signaling pathway
- Source :
- Translational Oncology; September 2024, Vol. 47 Issue: 1
- Publication Year :
- 2024
-
Abstract
- •KLF12 showed a negative correlation with progesterone receptor (PGR) expression in EC.•KLF12 decreases progesterone sensitivity by inhibiting the PGR signaling pathway.•KLF12 directly binds to the PGR promoter region.
Details
- Language :
- English
- ISSN :
- 19447124 and 19365233
- Volume :
- 47
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Translational Oncology
- Publication Type :
- Periodical
- Accession number :
- ejs66702802
- Full Text :
- https://doi.org/10.1016/j.tranon.2024.102041