Back to Search Start Over

Global prevalence of hereditary thrombotic thrombocytopenic purpura determined by genetic analysis

Authors :
Seidizadeh, Omid
Cairo, Andrea
Mancini, Ilaria
George, James N.
Peyvandi, Flora
Source :
Blood Advances; August 2024, Vol. 8 Issue: 16 p4386-4396, 11p
Publication Year :
2024

Abstract

•ADAMTS13exome/genome data from 807 162 gnomAD population was analyzed to establish worldwide/within-population prevalence of hereditary TTP.•Hereditary TTP prevalence is substantially higher than currently estimated, suggesting that many patients are not diagnosed.

Details

Language :
English
ISSN :
24739529 and 24739537
Volume :
8
Issue :
16
Database :
Supplemental Index
Journal :
Blood Advances
Publication Type :
Periodical
Accession number :
ejs66768116
Full Text :
https://doi.org/10.1182/bloodadvances.2024013421