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Clinical Practice Recommendations for Hematopoietic Cell Transplantation and Cellular Therapies in Follicular Lymphoma: A Collaborative Effort on behalf of The American Society of Transplantation and Cellular Therapy and the European Society of Blood and Marrow Transplantation

Authors :
Iqbal, Madiha
Kumar, Ambuj
Dreger, Peter
Chavez, Julio
Sauter, Craig S.
Sureda, Anna M.
Bachanova, Veronika
Maziarz, Richard T.
Dreyling, Martin
Smith, Sonali M.
Jacobson, Caron
Glass, Bertram
Casulo, Carla
Oluwole, Olalekan O.
Montoto, Silvia
Advani, Ranjana
Cohen, Jonathon
Salles, Gilles
Hamad, Nada
Kuruvilla, John
Kahl, Brad S.
Shadman, Mazyar
Kanate, Abraham S.
Budde, L. Elizabeth
Kamdar, Manali
Flowers, Christopher
Hamadani, Mehdi
Kharfan-Dabaja, Mohamed A.
Source :
Transplantation and Cellular Therapy; 20240101, Issue: Preprints
Publication Year :
2024

Abstract

•Autologous-HCT is recommended as an option for consolidation therapy in patients with progression of disease within 24 months of receiving front line chemoimmunotherapy and who do not have evidence of histological transformation and achieve a CR or PR to salvage second line therapy.•CAR-T should be considered a treatment option for patients who do not achieve CR or PR after second or subsequent lines of therapy.•Allogeneic-HCT can be considered as consolidative treatment in select cases of relapsed chemosensitive FL patients who have received 3 or more lines of systemic therapy and are in the following clinical scenarios: post CAR-T failure; lack of access to CAR-T; concomitant therapy related myeloid neoplasm or bone marrow failure syndrome.

Details

Language :
English
ISSN :
26666375 and 26666367
Issue :
Preprints
Database :
Supplemental Index
Journal :
Transplantation and Cellular Therapy
Publication Type :
Periodical
Accession number :
ejs66848095
Full Text :
https://doi.org/10.1016/j.jtct.2024.06.025