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Association of busulfan exposure and outcomes after HCT for patients with an inborn error of immunity
- Source :
- Blood Advances; October 2024, Vol. 8 Issue: 19 p5137-5145, 9p
- Publication Year :
- 2024
-
Abstract
- •In patients with IEI, improved EFS and higher donor chimerism may be achieved by targeting a cumulative busulfan AUC of 80 mg × h/L.•The data stress the importance of uniformly using a validated population pharmacokinetic model to estimate the busulfan cumulative exposure.
Details
- Language :
- English
- ISSN :
- 24739529 and 24739537
- Volume :
- 8
- Issue :
- 19
- Database :
- Supplemental Index
- Journal :
- Blood Advances
- Publication Type :
- Periodical
- Accession number :
- ejs67044792
- Full Text :
- https://doi.org/10.1182/bloodadvances.2024013275