Advancing Blood Flow in Stenotic Arteries through Magnetohydrodynamic Peristaltic Motion of Hybrid Nanoparticles

•Objective and approach: The research aims to evaluate the effectiveness of hybrid nanoparticles in improving magnetohydrodynamic (MHD) peristaltic blood flow in stenotic arteries through theoretical modeling and numerical simulations.•Nanoparticle Composition: Integration of Cu-Al2O3 nanoparticles into blood creates a homogeneous hybrid suspension, enhancing blood flow.•Mathematical Modeling: The study uses stenosis and non-dimensional parameter approximations to simplify coupled nonlinear partial differential equations and provides analytical solutions for blood flow parameters using perturbation techniques.•Blood flow parameters: Analyzing blood flow parameters such as velocity, temperature, stream function, wall shear stress, Nusselt number, and flow resistance impedance can reveal how hybrid nanoparticles impact these factors.•Physiological Impacts: The research shows that hybrid nanoparticles can reduce wall shear stress, increase axial flow speed, and improve velocity profile, reducing the negative effects of vascular stenosis and aiding narrowed arteries.