Silk fibroin–gelatine haemostatic sponge loaded with thrombin for wound haemostasis and tissue regeneration

Graphical AbstractSFG composite haemostatic sponges were prepared using gelatine and silk fibroin, which can address the mechanical defects of gelatine and silk fibroin when used alone.Adding thrombin can further improved the haemostatic performance of the SFG@TB composite haemostatic sponge.The SFG@TB composite hemostatic sponge with outstanding mechanical properties, good hemostatic performance and high biosafety can promote wound hemostasis and tissue repair.