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The hepcidin-ferroportin axis modulates liver endothelial cell BMP expression to influence iron homeostasis in mice
- Source :
- Blood; 20240101, Issue: Preprints
- Publication Year :
- 2024
-
Abstract
- •Liver endothelial cell (LEC) ferroportin modulates cellular iron and BMP ligand expression to influence hepcidin and systemic iron levels•Hepcidin regulates LEC ferroportin suggesting bidirectional crosstalk between LECs and hepatocytes to fine-tune systemic iron homeostasis
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- Blood
- Publication Type :
- Periodical
- Accession number :
- ejs67802675
- Full Text :
- https://doi.org/10.1182/blood.2024024795