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A Practical Mild, One-Pot, Regiospecific Synthesis of 2,3-Disubstituted Indoles via Consecutive Sonogashira and Cacchi Reactions

Authors :
Z. Lu, Bruce
Zhao, Wenyi
Wei, Han-Xun
Dufour, Marine
Farina, Vittorio
H. Senanayake, Chris
Source :
Organic Letters; July 2006, Vol. 8 Issue: 15 p3271-3274, 4p
Publication Year :
2006

Abstract

A practical one-pot, regiospecific three-component process for the synthesis of 2,3-disubstituted indoles was developed via consecutive Pd-catalyzed Sonogashira coupling, amidopalladation, and reductive elimination.

Details

Language :
English
ISSN :
15237060 and 15237052
Volume :
8
Issue :
15
Database :
Supplemental Index
Journal :
Organic Letters
Publication Type :
Periodical
Accession number :
ejs9524456
Full Text :
https://doi.org/10.1021/ol061136q