Intraoral fluoride delivery systems during orthodontic treatment

Introduction: There are different fluoride regimens aimed to reduce caries during orthodontic treatment with fixed appliances. Due to unpredictable compliance, there is a need for a long-term low-dose fluoride release delivery system. The aim of this study was to evaluate reported fluoride regimes in current use. Materials and Methods: The literature search with keywords „fluoride release orthodontic“was reached through PubMed website (US National Library of Medicine, National Institute of Health). The literature search with keywords „polycaprolactone fluoride“ was done through the same website, as well. Results: A total of 132 published studies reported fluoride use during orthodontic treatment with fixed appliances. Twenty five studies were dealing with wire corrosion and ion release, reviews and other topics, and were excluded from further analysis. One hundred and seven studies used 6 different sources of fluoride for orthodontic treatment with fixed appliances. The most used were orthodontic adhesives (70%) followed by topical fluorides (10%), elastomeric ligatures (7%), fluoride sustained release devices (6%), removable appliances and retainers (5%) and coated wires or brackets (2%). The literature search on polycaprolactone fluoride revealed 18 relevant studies. Among those, there were stuides about developing new clinical applications of polycprolactone flouride, with existing laboratory methods for incorporation and release of fluorides in/from polycaprolactone flouride. Conclusions: Intraoral fluoride release delivery systems take a small part in caries prevention. There is a need for improvement of existing and development of new fluoride release delivery systems. Polycaprolactone is promising material for sustained fluoride release.