Sporadic Creutzfeldt Jakob disease in patient with episodes of nonconvulsive status epilepticus : case report

Creutzfeldt Jakob disease (CJD) is the most common form of human prion diseases. A 57 year old woman was transferred to our Department from a local hospital, where she was treated for two weeks due to consciousness disorders and convulsive epileptic attacks that were progressed to refractory status epilepticus. Th e electroencephalography showed diff use outbreak spike- wave complexes and a development of nonconvulsive status epilepticus. We excluded the causes of metabolic encephalopathy and a paraneoplastic syndrome. Using a combination of clinical features and the fi ndings of diagnostic procedures, including electroencephalography, biomarkers in the cerebrospinal fl uid and MRI fi ndings, we could conclude with great probability that patient was aff ected with sCJD.