Function/structure correlation in novel pH-dependent cationic liposomes for glioma cells transfection in vitro

Authors :: Esposito C. 1
Masotti A. 2
Del Grosso N. 3
Malizia D. 4
Bianco A. 5
Bonadies F. 6
Napolitano R. 7
Ortaggi G. 8
Mossa G. 9
Source :: 6 (2003): 617–622., info:cnr-pdr/source/autori:Esposito C. 1, Masotti A. 2, Del Grosso N. 3, Malizia D. 4, Bianco A. 5, Bonadies F. 6, Napolitano R. 7, Ortaggi G. 8, Mossa G. 9/titolo:Function%2Fstructure correlation in novel pH-dependent cationic liposomes for glioma cells transfection in vitro/doi:/rivista:/anno:2003/pagina_da:617/pagina_a:622/intervallo_pagine:617–622/volume:6
Publication Year :: 2003
Abstract: Cationic liposomes are good candidates as gene carriers in cell biology due to their ability to bind DNA through electrostatic interactions. These molecules are used as non-viral delivery systems in the gene therapy of glioma. pH-dependency and transfection efficiency of seven novel lipids (MORF-1, MORF-2, MORF-3, PIPR-1, PIPR-2, MM54 and DC-Amy) were studied. Two of these molecules (PIPR-2 and MM54) show a better transfection efficiency than that of some commercially available liposomes.

Database :: OpenAIRE
Journal :: 6 (2003): 617–622., info:cnr-pdr/source/autori:Esposito C. 1, Masotti A. 2, Del Grosso N. 3, Malizia D. 4, Bianco A. 5, Bonadies F. 6, Napolitano R. 7, Ortaggi G. 8, Mossa G. 9/titolo:Function%2Fstructure correlation in novel pH-dependent cationic liposomes for glioma cells transfection in vitro/doi:/rivista:/anno:2003/pagina_da:617/pagina_a:622/intervallo_pagine:617–622/volume:6
Accession number :: edsair.cnr...........62a8a51739ae41cb48cde6599bd96024

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