Perinatal changes in fetal ventricular geometry, myocardial performance and cardiac function in normal term pregnancies

Background: The fetal heart at term is exposed to an increase in hemodynamic work as a consequence of fetal growth, increased circulating volume and alteration in loading patterns due to maturational changes in fetoplacental circulation. The extent to which these cardiovascular changes influence the human fetal and neonatal cardiac adaptation has not been fully elucidated. The aim of this study was to evaluate perinatal cardiovascular changes in ventricular geometry and myocardial performance in normal term fetuses.\ud \ud Methods: Prospective study of 108 uncomplicated pregnancies delivering at term. M-mode, twodimensional (2D) or B-mode, pulsed wave (PW) Doppler, PW tissue Doppler and 2D speckle\ud tracking imaging were performed a few days before, and within 24 hours of birth.\ud \ud Results: Analysis of paired fetal and neonatal echoes demonstrated significant perinatal changes (p