Recommendations by the Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and the Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) on vaccination in general and specifically against SARS-CoV-2 for patients with demyelinating diseases of the central nervous system

Made available in DSpace on 2022-04-29T08:46:09Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-01 The Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) provide recommendations in this document for vaccination of the population with demyelinating diseases of the central nervous system (CNS) against infections in general and against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19. We emphasize the seriousness of the current situation in view of the spread of COVID-19 in our country. Therefore, reference guides on vaccination for clinicians, patients, and public health authorities are particularly important to prevent some infectious diseases. The DCNI/ABN and BCTRIMS recommend that patients with CNS demyelinating diseases (e.g., MS and NMOSD) be continually monitored for updates to their vaccination schedule, especially at the beginning or before a change in treatment with a disease modifying drug (DMD). It is also important to note that vaccines are safe, and physicians should encourage their use in all patients. Clearly, special care should be taken when live attenuated viruses are involved. Finally, it is important for physicians to verify which DMD the patient is receiving and when the last dose was taken, as each drug may affect the induction of immune response differently. Pontifícia Universidade Católica Do Rio Grande Do Sul, RS Universidade Federal de Sergipe, SE Universidade Tiradentes, SE Universidade de Campinas Faculdade de Ciências Médicas, SP Universidade Federal de São Paulo Escola Paulista de Medicina, SP Universidade Federal de Minas Gerais, MG Universidade de São Paulo Faculdade de Medicina Hospital das Clínicas, SP Universidade Federal Do Amazonas, AM Universidade Federal Do Paraná, PR Hospital Sírio Libanês, SP Escola Bahiana de Medicina e Saúde Pública, BA Hospital Geral de Fortaleza, CE Clínica Nossa Senhora das Graças, MS Hospital Santa Marcelina, SP Santa Casa, MG Instituto de Infectologia Emílio Ribas, SP Fundação Centro Integrado de Apoio Ao Portador de Deficiência, PB Secretaria de Estado da Saúde, DF Universidade Federal Do Rio de Janeiro, RJ Santa Casa, PR Hospital de Clínicas de Passo Fundo, RS Universidade Federal de Goiás, GO Universidade Estácio de Sá, RJ Hospital São Francisco Na Providência de Deus, RJ Universidade Federal Do Ceará, CE Associação Brasileira de Esclerose Múltipla, SP Santa Casa, SP Universidade Federal Fluminense, RJ Pontifícia Universidade Católica, SP Instituto de Neurologia de Curitiba, PR IAMSPE, SP Private Service, SP Universidade da Região de Joinville, SC Hospital Moinhos de Vento, RS Santa Casa, RJ Universidade Federal Ciências da Saúde de Porto Alegre, RS Faculdade de Medicina de Jundiaí, SP Hospital Israelita Albert Einstein, SP Hospital de Base Do Distrito Federal, DF Hospital Beneficiência Portuguesa, SP Hospital Regional de Vilhena, RO Universidade Federal Do Estado Do Rio de Janeiro, RJ Hospital Universitário Prof. Edgar Santos, BA Universidade Metropolitana de Santos, SP Hospital da Restauração, PE Universidade Estadual Paulista Faculdade de Medicina de Botucatu, SP Universidade de Brasília Faculdade de Medicina, DF Universidade Estadual Paulista Faculdade de Medicina de Botucatu, SP