Back to Search
Start Over
Indium(III)-catalyzed synthesis of N-substituted pyrroles under solvent-free conditions
- Source :
- Journal of the Brazilian Chemical Society v.19 n.5 2008, Journal of the Brazilian Chemical Society, Sociedade Brasileira de Química (SBQ), instacron:SBQ, Journal of the Brazilian Chemical Society, Volume: 19, Issue: 5, Pages: 877-883, Published: 2008
- Publication Year :
- 2008
- Publisher :
- Sociedade Brasileira de Química, 2008.
-
Abstract
- A variety of N-substituted pyrroles have been synthesized by reacting γ-diketones (R¹C(O)CH2CH2C(O)R²: R¹, R² = Me, Ph) with amines (RNH2: R=Alkyl, Aryl, TsNH) or diamines (1,6-diaminohexane and 1,2-diaminoethane) in the presence of indium tribromide, indium trichloride or indium trifluoromethanesulfonate at room temperature under solvent-free conditions. The experiment protocol features simple operations, and the products are isolated in high to excellent yields (81-98%). Vários pirróis N-substituídos foram sintetizados pela reação de γ-dicetonas (R¹C(O)CH2CH2C(O)R²: R¹, R² = Me, Ph) com aminas (RNH2: R = Alkyl, Aryl, TsNH) ou diaminas (1,6-diaminohexano and 1,2-diaminoetano) na presença de tribrometo de índio, tricloreto de índio ou trifluorometanossulfonato de índio a temperatura ambiente e sem solventes. O protocolo envolve operações simples e os produtos são isolados em excelentes rendimentos (81-98%).
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Journal of the Brazilian Chemical Society v.19 n.5 2008, Journal of the Brazilian Chemical Society, Sociedade Brasileira de Química (SBQ), instacron:SBQ, Journal of the Brazilian Chemical Society, Volume: 19, Issue: 5, Pages: 877-883, Published: 2008
- Accession number :
- edsair.dedup.wf.001..193b9be48a54c61c23e92cd76e212a39