Running Head: Three-Dimensional Structure of the Brain Arteries

Aim: The aim of this study was to expose three-dimensional anatomy and projection of brain arteries used by injection-corrosion cast's technique. Although corrosion method previously was used to expose coronary and testicular arteries, this is the first study that was applied to human brain arteries in details. Methods: Internal carotid arteries and basilar artery of fresh human brain cannulised and irrigated with warm water, after that filled with colored polyester mixture. For corrosion process, brains were kept in diluted sulphuric acid and then carefully cleaned with water. By this way tree-dimensional anatomy of brain arteries were exposed. Results: Injection-corrosion cast's technique resulted in deeper penetration of colored solutions into small cerebral vessels and provided good three-dimensional vision. Conclusion: Vascular structures are usually discovered by cadaveric dissection method. By cadaveric dissection method, could obtain information about the origin of vascular structure but it is not possible for the anatomic position and projection. With the method of injection-corrosion, vascular structure could be exposed as tree-dimensional projection, even in the smallest branch look like it is in cranium position. From our point of view this technique will provide significant contribution to neurosurgery training and subsequent studies.