Back to Search Start Over

Decision making factors of the management of ductal carcinoma in situ of the breast with microinvasion

Authors :
Bouter, Jordan
Geffrelot, Julien
Danhier, Serge
Levy, Christelle
Le Brun, Jean-François
Hanzen, Chantal
Kirova, Youlia
Thariat, Juliette
Institut Curie
Laboratoire de physique corpusculaire de Caen (LPCC)
Université de Caen Normandie (UNICAEN)
Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN)
Normandie Université (NU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
Institut Curie [Paris]
Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)
Source :
Bull.Cancer, Bull.Cancer, 2019, 106 (11), pp.1000-1007. ⟨10.1016/j.bulcan.2019.05.005⟩
Publication Year :
2019
Publisher :
HAL CCSD, 2019.

Abstract

International audience; IntroductionMicroinvasive in situ ductal carcinomas of the breast are rare and of good prognosis. They are grouped with early stage invasive carcinomas in the TNM 2017 classification. This study assessed practitioners’ treatment decisions and their justifications in comparison to the literature.Materials and methodsThree clinical cases were evaluated by anonymous forms regarding sentinel node decisions, tumour bed boost irradiation and hormone therapy.ResultsSentinel lymph node was performed by 93.1%, 100% and 44.4% of the practitioners respectively. Radiation boost was a treatment option chosen by 62.1% and 61.1% of practitioners in both clinical cases. Hormone therapy was advocated for 65.5%, 94.7% and 50.0% patients depending on the clinical case.ConclusionThe therapeutic attitude proposed in microinvasive breast carcinomas was heterogeneous in this study, reflecting the absence of specific recommendations. In view of the existing literature, it is not currently possible to propose recommendations for these three therapeutic options. Prospective cohorts and meta-analyses of the microinvasive subgroup could provide answers.

Subjects

Subjects :
[PHYS]Physics [physics]

Details

Language :
English
Database :
OpenAIRE
Journal :
Bull.Cancer, Bull.Cancer, 2019, 106 (11), pp.1000-1007. ⟨10.1016/j.bulcan.2019.05.005⟩
Accession number :
edsair.dedup.wf.001..227a5720ee0fb97c90c9a1fca313eda7
Full Text :
https://doi.org/10.1016/j.bulcan.2019.05.005⟩