Ventilation practices in burn patients-an international prospective observational cohort study

Background: It is unknown whether lung-protective ventilation is applied in burn patients and whether they benefit from it. This study aimed to determine ventilation practices in burn intensive care units (ICUs) and investigate the association between lung-protective ventilation and the number of ventilator-free days and alive at day 28 (VFD-28). Methods: This is an international prospective observational cohort study including adult burn patients requiring mechanical ventilation. Low tidal volume (V-T) was defined as V-T = 5 cmH(2)O; 80% of patients had maximum airway pressures Funding Agencies|Nederlandse Brandwonden Stichting (the Dutch Burn Association, Beverwijk, The Netherlands)Netherlands Government