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Ciprofloxacin resistance in bacteria from a wastewater treatment plant:Combining genomics and metabolomics to identify Ciprofloxacin-tolerant strains by 16S amplicon sequencing
- Source :
- Aggerbeck, M R, Hansen, M, Johansen, A, Gobbi, A, Ellegaard-Jensen, L & Hansen, L H 2019, ' Ciprofloxacin resistance in bacteria from a wastewater treatment plant : Combining genomics and metabolomics to identify Ciprofloxacin-tolerant strains by 16S amplicon sequencing ' .
- Publication Year :
- 2019
-
Abstract
- Ciprofloxacin, a fluoroquinolone-type broad spectrum antibiotic, was found to persist through wastewater treatment. This raises questions on how an antibiotic affects the native microbial community of wastewater treatment plants, and if this – in addition to hampering treatment – inadvertently contributes to antibiotic resistance; a continuing, severe challenge to medical procedures and treatment. We investigated isolates from the activated sludge communities in a Danish wastewater treatment plant to determine any ciprofloxacin-tolerant species, and discovered a number of strains able to grow when exposed to various concentrations of the drug.
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Aggerbeck, M R, Hansen, M, Johansen, A, Gobbi, A, Ellegaard-Jensen, L & Hansen, L H 2019, ' Ciprofloxacin resistance in bacteria from a wastewater treatment plant : Combining genomics and metabolomics to identify Ciprofloxacin-tolerant strains by 16S amplicon sequencing ' .
- Accession number :
- edsair.dedup.wf.001..31af5462b2f52bf04c8a20d33f6fb95e